We provide the most comprehensive range of peptide modifications available, including the following popular items:

Click Chemistry – including azido-containing and alkyne-containing components.  We also offer Huisgen 1,3-dipolar cycloaddition,1 in particular the Cu(I)-catalyzed variant.

15N & 13C Isotope labeled peptides – non-radioactive isotope labeling

Dye labeled peptides
– full range of dyes available, yellow, green, purple, red, etc.

Fluorescent peptides
– important tools in biochemical and biological research to study interactions between proteins, to analyze conformational structures, to design substrates, etc.

Phospho peptides (phosphorylated)
– Ser, Thr, and Tyr phosphorylation sites available

Biotin labeled peptides – biotinylation via either the sulfhydryl (SH) group, or amino group (NH2), with or without a spacer (Ahx)

Fatty Acid labeled peptides – Palmitoyl, myristoyl, capryl, carnosine, octyl, octyl-carnonine, carnosine-octylester, etc.

Disulfide Bond containing peptides Important structure motifs, achieved by the oxidation of thiol groups to form disulfide bonds

Citrulline (and derivatives) 

FRET Pairing:  Modification Spotlight: FRET Pairing info  (Fluorescence Resonance Energy Transfer)

Please contact us directly for any peptide modification you do not see listed, as this is just a sample of the many peptide modifications we offer.

Modification
Price
Acetylation (N-Terminal)
Free
Acetylation (Lys)
$95
Formylation (N-Terminal)
$195
Fatty acid (N-Terminal)
$95
Myristic acid (N-Terminal)
$95
Palmitoyl/Palmitic Acid
(N-Terminal)
$95
Cys(Acm), Cys(tBu)
$95, $250
Benzyloxycarbonylation (CBZ)
$50
Amidation (C-Terminal)
Free
p-Nitroanilide (pNA, C-Terminal)
Inquire
AMC ( C-Terminal)
$295
Succinylation (Suc, N-Terminal)
$50
NHS (OSu, C-Terminal)
$295
CMK/FMK (C-Terminal)
Inquire
Special amino acid
 
D-IleGamma-Glu, beta-Asp
Inquire
D-Arg, D-Cys, D-Asp, D-Asn, D-Glu,   D-Gln, D-Ser, D-His, D-Thr, D-Trp, D-Lys, D-Tyr, D-Orn, Orn, Abu, Aib, (D)1-Nal, (D)2-Pal, (D)4-Cl-Phe, Nva, Nle, Hse, Hcy, Pen, Mpa
Inquire
N-Methyl amino acid
(Ala, Phe, Leu, Ile, Val, Gly, Met)
Inquire
D-Ala, D-Leu, D-Met, D-Pro, D-Val,
D-Phe, -Ala, pGlu, Hyp
Inquire
Dinitrobenzoylation (Lys)
Inquire
Lys(Me2)
Inquire
Phosphorylation
(Tyr, Ser, Thr, single site)
$175
Tyr(SO3H2)
$150
Ser(octanoic acid)
Inquire
Isotope Amino acid
 
Stable label amino acid (N15, C13)
Inquire
Fluorescence/Dye Labeling
 
Biotin (N-Terminal, Y/N Ahx)
$60
Biotin (Lys in sequence)
$195
Biotin (without Lys in sequence)
$250
FITC/5-FAM (N-Terminal, Y/N Ahx)
$175
Dansyl (N-Terminal, Y/N Ahx)
$175
MCA (N-Terminal)
$250
HYNIC (N-Terminal)
$250
DTPA (N-Terminal)
Inquire
Cyclic peptide
 
Disulfide bridge 1st
$175
Disulfide bridge 2nd
Inquire
Disulfide bridge 3rd
Inquire
Amide cyclic (Side chain, end)
Inquire
Quenched fluorescent peptide
 
Abz/ Tyr (3-NO2)
Inquire
EDANS or DABCYL
Inquire
MultipleAntigenicPeptide System
0-20mg
Asymmetric 4 branches
inquire
Asymmetric 8 branches
inquire
Crude peptide w/ HPLC analysis
KLH
$195
BSA
$195
Aliquoting
$2/vial
Amino Acid Analysis (AAA) by 
 Nitrogen
USD200/peptide

 

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