Peptide library services start as low as $25/peptide for a RS-PEPSET™ library.

Peptide library Flexible Processes and high-throughput synthesis equipment enable us to offer ultra-competitive pricing, quick delivery, and high yields. Peptide library services for both small and large libraries are easily synthesized. Popular libraries include:

Overlapping (shown), Alanine Scan, Positional Scan, Random, Scrambled, Truncation, and Di-peptide Libraries. Perfect for:

  • Epitope mapping studies
  • Vaccine research
  • HT protein-protein interaction analysis
  • Customized peptide microarray production
  • Kinase assays
  • Novel drug stucture studies

We can also incorporate most typical peptide modifications in our peptide library services, such as unusual amino acids, D-amino acids, C-terminal amidation, N-terminal modification, and biotin, dye or fluorescence labeling on the N-terminal or lysine side chains.

Peptide Library Specifications

  • Any number of peptides (no minimum)
  • Any peptide length
  • Any quantity (1mg minimum)
  • Modifications available
  • HPLC and Mass spec can be included for every peptide
  • Crude or Purified, Cleaved or Uncleaved from the Resin
  • Free peptide library generation
Flexible packaging solutions

  • Standard vials
  • 12/48/96 Well Plates
  • User defined, custom packaging

Peptide libraries

Scanning Peptide Library Services

Alanine Scanning libraries are most common, although scanning libraries of other amino acids have been reported. In alanine scanning libraries, each amino acid in the peptide sequence is individually replaced by alanine. Alanine scans are useful for identifying essential residues within the peptide. When an essential residue is replaced with alanine, the corresponding peptide shows markedly reduced activity.

Truncation Peptide Library Services

In truncation peptide libraries, the peptide sequence is systematically shortened from the N-terminal or C-terminal. Truncation libraries are useful for identifying the minimum peptide length required for activity. Truncation libraries can be useful in studying the metabolic degradation of peptide drugs.

Scrambled Peptide Library Services

Scrambled peptide libraries are prepared through permutation of the original peptide sequence. Scrambled libraries can provide valuable information for sequence optimization.

Combinatorial Peptide Library Services

Combinatorial peptide libraries, in their broadest form, contain every possible peptide of a specific length; therefore, they are useful for drug discovery and research. Combinatorial libraries are prepared by systematically substituting every amino acid at each position in the sequence. Since the number of possible peptides can become astronomical, combinatorial libraries are often constrained by strictly limiting the number of amino acids used in creating the library or limiting the number of positions that are substituted. When only a few positions are randomized, the library is called a Positional Scanning Library.

Positional Scanning Peptide Library Services

In positional scanning peptide libraries, every amino acid is systematically substituted into a specified position in a peptide. Positional scanning libraries are highly constrained versions of combinatorial libraries. They are useful for sequence optimization.

Overlapping Peptide Library Services

Overlap peptide libraries are used in mapping linear epitopes. Overlap libraries are characterized by the fragment length and overlap number

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